Description

(+)-Bicifadine Hydrochloride CAS NO 66504-82-3 is the active pharmaceutical ingredient (API) form of a selective serotonin and norepinephrine reuptake inhibitor (SSNRI). This compound is of significant interest for its potential therapeutic applications in central nervous system disorders. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and API manufacturers engaged in the development of novel analgesic and neuropsychiatric medications.

Application

• Pharmaceutical research and development of novel non-opioid analgesic agents.
• Preclinical and clinical studies targeting chronic pain management.
• Investigational drug substance for neuropathic pain and fibromyalgia research.
• Reference standard for analytical method development and validation in QC laboratories.
• Active Pharmaceutical Ingredient (API) for formulation studies in dosage form development.
• Biochemical research focusing on monoamine transporter inhibition mechanisms.

Basic Information

Product Name	(+)-Bicifadine Hydrochloride
CAS No.	66504-82-3
Molecular Formula	C17H25NO2 • HCl
Molecular Weight	311.85 g/mol
Synonyms	(+)-Bicifadine HCl; (1S,2R)-rel-1-(3,4-Dichlorophenyl)-3-azabicyclo[3.1.0]hexan-2-yl]methanol Hydrochloride; DW-224a; Bicifadine Hydrochloride (enantiomer); (1S,2R)-1-(3,4-Dichlorophenyl)-3-azabicyclo[3.1.0]hexane-2-methanol Hydrochloride
EINECS	Contact for details

Quality Control

Our (+)-Bicifadine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including identification, assay, impurity profiling, and residual solvent analysis to ensure it meets stringent specifications for pharmaceutical research. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance with your research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Any single unknown impurity	≤0.5%
Optical Rotation	[α]20/D: Contact for details
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.