Description

1-Iodobutane-4,4,4-D3 is a deuterium-labeled isotopologue of 1-iodobutane, a valuable building block in synthetic organic chemistry. Its primary value lies in its utility as a stable, non-radioactive isotopic tracer, enabling detailed mechanistic studies and metabolic pathway analysis in pharmaceutical and agrochemical research. This compound is essential for researchers and process chemists in the pharmaceutical, biotechnology, and advanced materials sectors who require high-purity, isotopically enriched intermediates for labeling experiments and spectroscopic standards.

Application

• Deuterium-Labeled Intermediate: Serves as a crucial precursor for the synthesis of more complex deuterated molecules in medicinal chemistry and drug discovery.
• Mechanistic Probe: Used in kinetic isotope effect (KIE) studies to elucidate reaction mechanisms and pathways in organic synthesis.
• Internal Standard: Employed as an internal standard in quantitative mass spectrometry (MS) and nuclear magnetic resonance (NMR) spectroscopy for accurate analyte measurement.
• Metabolic Research: Facilitates the tracing of metabolic pathways and the study of drug metabolism and pharmacokinetics (DMPK) in preclinical research.
• Material Science: Used in the development of specialty polymers and organic electronic materials where isotopic labeling can modify physical properties.

Basic Information

Product Name	1-Iodobutane-4,4,4-D3
CAS No.	66502-74-7
Molecular Formula	C4H6D3I
Molecular Weight	200.02 g/mol
Synonyms	Butyl-d3 Iodide; 4,4,4-Trideuterio-1-iodobutane; n-Butyl-d3 Iodide; 1-Iodo-4,4,4-trideuteriobutane; Deuterated n-Butyl Iodide; [D3]-1-Iodobutane; Perdeuterated Butyl Iodide (partial); 1-Iodobutane-d3
EINECS	Contact for details

Quality Control

Our 1-Iodobutane-4,4,4-D3 is manufactured under strict quality control protocols to ensure high isotopic and chemical purity suitable for sensitive research applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing parameters such as isotopic enrichment (D atom %), chemical purity by GC, and identity confirmation by NMR and/or IR spectroscopy. We adhere to cGMP principles for the production of labeled compounds to ensure batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. Due to its light-sensitive nature and potential volatility, containers should be kept sealed and handled under an inert atmosphere when appropriate for prolonged storage.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Isotopic Enrichment (NMR/MS)	≥ 98 atom % D
Water Content (KF)	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.