Description

6-Chlorobenzo[B]Thiophene is a halogenated heterocyclic compound that serves as a versatile and critical building block in advanced organic synthesis. Its value lies in its ability to introduce the benzo[b]thiophene core, a privileged scaffold in medicinal chemistry and materials science, with a reactive chlorine handle for further functionalization. This intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of drug candidates targeting various therapeutic areas, leveraging the benzo[b]thiophene scaffold's bioactivity.
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and insecticides with enhanced efficacy.
• Material Science Research: Used in the development of organic semiconductors, conductive polymers, and non-linear optical (NLO) materials.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological systems and enzyme mechanisms.
• Dye and Pigment Intermediate: Acts as a precursor in the production of specialized dyes and high-performance pigments.

Basic Information

Product Name	6-Chlorobenzo[B]Thiophene
CAS No.	66490-20-8
Molecular Formula	C8H5ClS
Molecular Weight	168.64 g/mol
Synonyms	6-Chlorobenzo[b]thiophene; 6-Chloro-1-benzothiophene; 6-Chloro-benzo[b]thiophene; 6-Chloro-1-benzothiophene; Benzo[b]thiophene, 6-chloro-; 6-Chlorobenzo(b)thiophene
EINECS	Contact for details

Quality Control

Our 6-Chlorobenzo[B]Thiophene is manufactured under strict quality management protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC purity, identity confirmation (IR, NMR), and impurity profiling. A Certificate of Analysis (COA) is supplied with each shipment, detailing all relevant specifications. Our quality systems support development and commercial scale requirements for the pharmaceutical and fine chemical industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.