Description

2,5-Piperazinedione,1,3,4-Trimethyl-,(R)-(9Ci) is a chiral, non-proteinogenic amino acid derivative belonging to the piperazinedione class, which is a key structural motif in many bioactive compounds. This specific stereoisomer is valued for its role as a sophisticated building block in the synthesis of complex pharmaceuticals and advanced research chemicals. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for creating novel active ingredients and chiral catalysts.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and development of new drug candidates, particularly in oncology and neurology.
• Peptidomimetic Research: Serves as a constrained scaffold in the design of peptide analogs to enhance metabolic stability and bioavailability.
• Asymmetric Synthesis: Utilized as a precursor or auxiliary in the synthesis of enantiomerically pure compounds for high-value applications.
• Agrochemical Development: Employed in the creation of novel, chiral active ingredients for crop protection products.
• Ligand and Catalyst Preparation: Used to develop specialized ligands for metal-catalyzed reactions in fine chemical manufacturing.
• Academic and Industrial R&D: A valuable reference standard and starting material for methodological studies in organic and medicinal chemistry.

Basic Information

Product Name	2,5-Piperazinedione,1,3,4-Trimethyl-,(R)-(9Ci)
CAS No.	66445-42-9
Molecular Formula	C7H12N2O2
Molecular Weight	156.18 g/mol
Synonyms	(R)-1,3,4-Trimethyl-2,5-piperazinedione; (R)-1,3,4-Trimethylpiperazine-2,5-dione; (3R)-1,3,4-Trimethylpiperazine-2,5-dione; L-1,3,4-Trimethyl-2,5-piperazinedione; (R)-1,3,4-Trimethyl-2,5-diketopiperazine; (R)-TMPD; (R)-1,3,4-Trimethyl-DKP; 2,5-Diketopiperazine, 1,3,4-trimethyl-, (R)-
EINECS	Contact for details

Quality Control

Our 2,5-Piperazinedione,1,3,4-Trimethyl-,(R)-(9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.