Description

(+/-)-Amphetamine-D11 CAS NO 66432-30-2 is a deuterated internal standard of the psychostimulant amphetamine, where eleven hydrogen atoms are replaced with the stable isotope deuterium. This compound is critically important for ensuring accurate and reliable quantitative analysis in forensic, clinical, and pharmaceutical research. It is primarily needed by analytical laboratories and research institutions conducting mass spectrometry-based assays for drug testing, pharmacokinetic studies, and the development of diagnostic methods.

Application

• Internal Standard for Mass Spectrometry (MS): Used as a quantitative reference in GC-MS and LC-MS/MS analysis of amphetamine and its metabolites in biological matrices.
• Forensic Toxicology: Essential for the precise quantification of amphetamine in urine, blood, and hair samples in drug testing and legal cases.
• Clinical Research: Supports pharmacokinetic and pharmacodynamic studies by enabling accurate measurement of drug concentrations in plasma and tissues.
• Pharmaceutical Development: Employed in the bioanalysis of drug candidates and in stability testing of pharmaceutical formulations.
• Method Validation & Quality Control: Serves as a critical component in validating analytical methods and ensuring the accuracy of laboratory results.
• Isotope Dilution Analysis: Used in high-precision analytical techniques to correct for sample loss and matrix effects during extraction.

Basic Information

Product Name	(+/-)-Amphetamine-D11
CAS No.	66432-30-2
Molecular Formula	C9D11N
Molecular Weight	145.27 g/mol
Synonyms	(±)-Amphetamine-d11; DL-Amphetamine-d11; 1-Phenyl-2-aminopropane-d11; α-Methylphenethylamine-d11; Benzedrine-d11; Racemic Amphetamine-d11; Deutetrated Amphetamine Internal Standard; Amphetamine (phenyl-d5, methyl-d6)
EINECS	Contact for details

Quality Control

Our deuterated standards, including (+/-)-Amphetamine-D11, are produced under strict quality systems to ensure the highest isotopic purity and chemical stability required for sensitive analytical applications. Each batch is rigorously tested by NMR and mass spectrometry to confirm isotopic enrichment and absence of protiated impurities. A comprehensive Certificate of Analysis (COA) is provided, detailing assay, isotopic purity, and chromatographic data. We support compliance with ISO/IEC 17025 standards for testing laboratories.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dedicated freezer. Due to its highly volatile nature, allow the vial to equilibrate to room temperature before opening to prevent moisture condensation. For long-term stability, store under an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (NMR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity	≥ 98 atom % D
Chemical Purity	≥ 95% (by NMR)
Solubility	Soluble in methanol, ethanol, acetonitrile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.