Description

7-Hydroxy-1,2,3,4-Tetrahydroisoquinoline Hydrochloride is a versatile organic salt and a key synthetic intermediate in advanced pharmaceutical chemistry. Its value lies in its role as a crucial building block for constructing complex nitrogen-containing heterocycles, which are foundational to numerous active pharmaceutical ingredients (APIs). This compound is essential for research and development chemists and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop new therapeutic agents or specialty chemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of various alkaloids and bioactive molecules with potential neurological or cardiovascular activity.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, leveraging its heterocyclic structure.
• Fine Chemical Production: Serves as a building block for creating complex ligands, catalysts, and specialty dyes.
• Academic & Contract Research: A valuable reagent for medicinal chemistry programs and pharmacological studies in university and CRO laboratories.
• Chemical Reference Standard: Employed as a high-purity standard for analytical method development and quality control in API manufacturing.

Basic Information

Product Name	7-Hydroxy-1,2,3,4-Tetrahydroisoquinoline Hydrochloride
CAS No.	66393-01-9
Molecular Formula	C9H12ClNO
Molecular Weight	185.65 g/mol
Synonyms	7-Hydroxy-1,2,3,4-tetrahydroisoquinoline HCl; 1,2,3,4-Tetrahydro-7-isoquinolinol hydrochloride; 7-Hydroxy-THIQ hydrochloride; 7-Hydroxy-1,2,3,4-tetrahydroisoquinoline monohydrochloride; 7-Hydroxy-3,4-dihydro-1H-isoquinoline hydrochloride; 7-Hydroxy-1,2,3,4-tetrahydroisoquinoline HCl salt; 7-OH-THIQ·HCl
EINECS	Contact for details

Quality Control

Our 7-Hydroxy-1,2,3,4-Tetrahydroisoquinoline Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.