Description

2-[(1α,4Z,8α)-9-Azabicyclo[6.1.0]Non-4-En-9-Yl]-1H-Isoindole-1,3(2H)-Dione is a sophisticated bicyclic organic compound that serves as a critical building block in advanced chemical synthesis. Its unique azabicyclo[6.1.0]nonene core fused with a phthalimide moiety makes it a valuable intermediate for constructing complex molecular architectures with specific stereochemistry. This high-purity intermediate is essential for research and development in pharmaceutical chemistry and advanced material science, where precise structural control is paramount.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and anti-infective drug candidates.
• Advanced Organic Synthesis: Used as a versatile scaffold for constructing complex, strained-ring systems and chiral ligands in asymmetric catalysis.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and the development of new chemical entities (NCEs) due to its constrained geometry.
• Chemical Biology Probes: Acts as a core structure for developing molecular probes to study enzyme function and biological pathways.
• Material Science Research: Investigated as a monomer or additive for creating polymers with unique thermal or mechanical properties.

Basic Information

Product Name	2-[(1α,4Z,8α)-9-Azabicyclo[6.1.0]Non-4-En-9-Yl]-1H-Isoindole-1,3(2H)-Dione
CAS No.	66387-75-5
Molecular Formula	C₁₉H₂₀N₂O₂
Molecular Weight	308.38 g/mol
Synonyms	9-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)-9-azabicyclo[6.1.0]non-4-ene; 9-Phthalimido-9-azabicyclo[6.1.0]non-4-ene; 2-(9-Azabicyclo[6.1.0]non-4-en-9-yl)isoindoline-1,3-dione; Azabicyclononene Phthalimide Derivative; Bicyclic Phthalimide Intermediate
EINECS	Contact for details

Quality Control

Our production of 2-[(1α,4Z,8α)-9-Azabicyclo[6.1.0]Non-4-En-9-Yl]-1H-Isoindole-1,3(2H)-Dione adheres to stringent quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment supports applications requiring high-purity chemical intermediates for regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound should be kept under an inert atmosphere if long-term storage is required to prevent potential degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.