Description

2-Phenyl-3-[1-(1H-Tetrazol-5-Yl)ethylthio]-1H-indole is a high-value, heterocyclic organic compound featuring a unique indole core fused with phenyl and tetrazole moieties via a thioether linkage. This complex molecular architecture makes it a critical advanced pharmaceutical intermediate (API) and a versatile scaffold for medicinal chemistry research. It is primarily sought after by R&D and production teams in the pharmaceutical and biotechnology sectors for the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of active pharmaceutical ingredients (APIs) targeting various disease pathways.
• Medicinal Chemistry Research: Used as a privileged scaffold for designing and synthesizing new chemical entities (NCEs) in drug discovery programs.
• Angiotensin II Receptor Antagonist Development: The tetrazole group is a known bioisostere for carboxylic acids, making this compound relevant for research into cardiovascular drugs like sartans.
• Chemical Biology Probes: Utilized in the development of molecular probes to study enzyme function and biological mechanisms.
• Organic Synthesis: Acts as a sophisticated precursor for synthesizing more complex heterocyclic compounds in academic and industrial laboratories.

Basic Information

Product Name	2-Phenyl-3-[1-(1H-Tetrazol-5-Yl)ethylthio]-1H-indole
CAS No.	66355-08-6
Molecular Formula	C₁₇H₁₅N₅S
Molecular Weight	321.40 g/mol
Synonyms	1H-Indole, 2-phenyl-3-[(1H-tetrazol-5-yl)ethylthio]-; 2-Phenyl-3-[(1H-tetrazol-5-yl)ethylthio]-1H-indole; 3-[(1H-Tetrazol-5-yl)ethylthio]-2-phenyl-1H-indole; 2-Phenyl-3-(1-(1H-tetrazol-5-yl)ethylthio)-1H-indole; 66355-08-6; Tetrazole-indole derivative; 1-(1H-Tetrazol-5-yl)ethyl 2-phenyl-1H-indol-3-yl sulfide
EINECS	Contact for details

Quality Control

Our production of 2-Phenyl-3-[1-(1H-Tetrazol-5-Yl)ethylthio]-1H-indole adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure high purity and structural integrity suitable for research and development applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.