Description

5-Methoxy-2-(4-Methoxyphenyl)-3-[(1H-Tetrazol-5-Yl)Methylthio]-1H-Indole is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of significant commercial value for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular design. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new chemical entities, offering a critical scaffold for drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the multi-step synthesis of complex drug molecules, especially those targeting specific receptors or enzymes.
• Drug Discovery Research: Used as a core scaffold in medicinal chemistry for the design and optimization of new chemical entities with potential therapeutic activity.
• Process Chemistry Development: Employed in route scouting and scale-up studies for the efficient and cost-effective production of target APIs.
• Contract Research & Manufacturing (CRAM): Supplied to CDMOs and CROs for custom synthesis projects and client-specific molecule production.
• Academic Research: Utilized in university and institutional labs for studying heterocyclic chemistry, reaction mechanisms, and structure-activity relationships (SAR).

Basic Information

Product Name	5-Methoxy-2-(4-Methoxyphenyl)-3-[(1H-Tetrazol-5-Yl)Methylthio]-1H-Indole
CAS No.	66355-06-4
Molecular Formula	C₁₈H₁₇N₅O₂S
Molecular Weight	367.42 g/mol
Synonyms	3-[(1H-Tetrazol-5-yl)methylthio]-5-methoxy-2-(4-methoxyphenyl)-1H-indole; 5-Methoxy-2-(4-methoxyphenyl)-3-[(1H-tetrazol-5-yl)methylthio]indole; 5-Methoxy-2-(4-methoxyphenyl)-3-[(1H-tetrazol-5-yl)methylthio]-1H-indole; 66355-06-4; 1H-Indole, 5-methoxy-2-(4-methoxyphenyl)-3-[(1H-tetrazol-5-yl)methylthio]-; 5-Methoxy-2-(4-methoxyphenyl)-3-[(1H-tetrazol-5-yl)methylsulfanyl]-1H-indole
EINECS	Contact for details

Quality Control

Our 5-Methoxy-2-(4-Methoxyphenyl)-3-[(1H-Tetrazol-5-Yl)Methylthio]-1H-Indole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical-grade intermediates. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical characteristics is provided with every shipment to support your quality and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound may be light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.