Description

2-(2,4-Dimethylphenyl)-3-[(1H-Tetrazol-5-Yl)Methylthio]-1H-Indole is a specialized heterocyclic compound featuring a unique indole core linked to a tetrazole moiety via a methylthio bridge. This molecular architecture makes it a valuable advanced pharmaceutical intermediate and a key building block in medicinal chemistry research. It is primarily sought after by pharmaceutical R&D and fine chemical synthesis sectors for developing novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, particularly those targeting specific enzyme pathways.
• Medicinal Chemistry Research: Used as a core scaffold or building block for structure-activity relationship (SAR) studies and lead optimization.
• Bioactive Molecule Synthesis: Employed in the development of compounds with potential biological activity, leveraging the tetrazole group as a bioisostere for carboxylic acids.
• Fine Chemical Production: Integral to multi-step synthetic routes for producing high-value, complex organic molecules in laboratory and pilot-scale operations.
• Contract Research & Manufacturing (CRAM): Supplied to organizations engaged in custom synthesis and process development for the life sciences industry.

Basic Information

Product Name	2-(2,4-Dimethylphenyl)-3-[(1H-Tetrazol-5-Yl)Methylthio]-1H-Indole
CAS No.	66355-03-1
Molecular Formula	C18H17N5S
Molecular Weight	335.42 g/mol
Synonyms	3-[(1H-Tetrazol-5-yl)methylthio]-2-(2,4-dimethylphenyl)-1H-indole; 2-(2,4-Dimethylphenyl)-3-[(1H-tetrazol-5-yl)methylthio]-1H-indole; 1H-Indole, 2-(2,4-dimethylphenyl)-3-[(1H-tetrazol-5-yl)methylthio]-; CAS 66355-03-1
EINECS	Contact for details

Quality Control

Our production of 2-(2,4-Dimethylphenyl)-3-[(1H-Tetrazol-5-Yl)Methylthio]-1H-Indole adheres to stringent quality protocols suitable for research and pharmaceutical intermediate applications. Every batch undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic identification (NMR, MS). A detailed Certificate of Analysis (COA) is provided with each shipment to ensure traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.