Description

2-(4-Methoxyphenyl)-3-[(1H-Tetrazol-5-Yl)Methylthio]-1H-Indole is a high-purity, advanced pharmaceutical intermediate featuring a unique molecular scaffold that combines indole and tetrazole pharmacophores. This compound matters for its critical role in the research and development of novel therapeutic agents, particularly as a key building block in medicinal chemistry. Pharmaceutical R&D laboratories and fine chemical manufacturers need this specialized intermediate for synthesizing potential drug candidates targeting a range of biological pathways.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for research into central nervous system (CNS) and anti-inflammatory agents.
• Medicinal Chemistry Research: Used as a scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs, leveraging its indole-tetrazole hybrid structure.
• Biochemical Tool Compound: Employed in biochemical assays and as a reference standard for studying enzyme inhibition or receptor binding activities in academic and industrial research settings.
• Fine Chemical Synthesis: Acts as a specialized building block for the custom synthesis of complex, high-value organic molecules for various research applications.

Basic Information

Item	Detail
Product Name	2-(4-Methoxyphenyl)-3-[(1H-Tetrazol-5-Yl)Methylthio]-1H-Indole
CAS No.	66355-01-9
Molecular Formula	C₁₇H₁₅N₅OS
Molecular Weight	337.40 g/mol
Synonyms	2-(4-Methoxyphenyl)-3-[(1H-tetrazol-5-yl)methylthio]-1H-indole; 3-[(1H-Tetrazol-5-yl)methylthio]-2-(4-methoxyphenyl)-1H-indole; 2-(4-Methoxyphenyl)-3-[(1H-tetrazol-5-yl)methylsulfanyl]-1H-indole; 66355-01-9; Tetrazole-indole derivative; Indole-tetrazole hybrid intermediate
EINECS	Contact for details

Quality Control

Our 2-(4-Methoxyphenyl)-3-[(1H-Tetrazol-5-Yl)Methylthio]-1H-Indole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the exacting standards required for pharmaceutical R&D. Certificates of Analysis (COA) with complete batch data are provided to guarantee traceability, consistency, and compliance with your research specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and handling properties. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.