Description

5-Chloro-2-Phenyl-3-[(1H-Tetrazol-5-Yl)Methylthio]-1H-Indole is a complex heterocyclic organic compound featuring a unique indole core substituted with a tetrazole-thioether moiety. This specific molecular architecture makes it a valuable advanced pharmaceutical intermediate and a key building block in medicinal chemistry research. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers for the development of novel therapeutic agents, particularly those targeting specific enzymatic pathways.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, especially those with indole and tetrazole pharmacophores.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Biologically Active Compound Synthesis: Employed in the development of compounds with potential anti-inflammatory, anticancer, or antimicrobial properties.
• Chemical Biology Probes: Acts as a building block for creating molecular probes to study enzyme function and biological pathways.
• Fine Chemical Production: Utilized in multi-step organic syntheses requiring high-purity, specialized intermediates.

Basic Information

Product Name	5-Chloro-2-Phenyl-3-[(1H-Tetrazol-5-Yl)Methylthio]-1H-Indole
CAS No.	66354-94-7
Molecular Formula	C₁₆H₁₂ClN₅S
Molecular Weight	341.82 g/mol
Synonyms	5-Chloro-2-phenyl-3-[(1H-tetrazol-5-yl)methylthio]-1H-indole; 3-[(1H-Tetrazol-5-yl)methylthio]-5-chloro-2-phenyl-1H-indole; 5-Chloro-2-phenyl-3-(1H-tetrazol-5-ylmethylsulfanyl)-1H-indole; 5-Chloro-2-phenyl-3-(1H-tetrazol-5-ylmethylthio)indole; 1H-Indole, 5-chloro-2-phenyl-3-[(1H-tetrazol-5-yl)methylthio]-; CAS 66354-94-7
EINECS	Contact for details

Quality Control

Our production of 5-Chloro-2-Phenyl-3-[(1H-Tetrazol-5-Yl)Methylthio]-1H-Indole adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. All materials undergo comprehensive analytical testing, including HPLC, NMR, and mass spectrometry. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.