Description

4-Thiazoleacetyl Chloride, 2-Amino-, Monohydrochloride is a high-purity, reactive chemical intermediate essential for advanced organic synthesis. Its value lies in its role as a key building block for constructing complex heterocyclic molecules, particularly in pharmaceutical research and development. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel thiazole-containing drug candidates, including potential antibiotics, antivirals, and enzyme inhibitors.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides that leverage the thiazole moiety for biological activity.
• Peptide Mimetics & Bioconjugation: The reactive acid chloride group enables its use in creating peptide analogs or for conjugating thiazole derivatives to other biomolecules.
• Material Science Research: Serves as a monomer or functionalization agent in the development of specialty polymers and advanced organic materials.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and target engagement.

Basic Information

Product Name	4-Thiazoleacetyl Chloride, 2-Amino-, Monohydrochloride
CAS No.	66313-72-2
Molecular Formula	C5H6Cl2N2OS
Molecular Weight	213.08 g/mol
Synonyms	2-Amino-4-thiazoleacetyl chloride hydrochloride; 2-Aminothiazole-4-acetyl chloride hydrochloride; (2-Amino-1,3-thiazol-4-yl)acetyl chloride hydrochloride; 4-Thiazoleacetic acid, 2-amino-, chloride, hydrochloride; 2-Amino-4-thiazolylacetyl chloride monohydrochloride; α-Chloro-2-amino-4-thiazoleacetamide hydrochloride (related); 66313-72-2
EINECS	Contact for details

Quality Control

Our 4-Thiazoleacetyl Chloride, 2-Amino-, Monohydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.