Description

4-(2,4-Dimethylphenyl)-4H-1,2,4-Triazole-3-Thiol is a specialized heterocyclic organic compound belonging to the 1,2,4-triazole class, distinguished by its thiol functional group and dimethylphenyl substituent. This structure makes it a valuable intermediate for synthesizing more complex molecules with targeted biological or material science properties. It is primarily sought by R&D chemists and process development teams in the pharmaceutical and agrochemical industries for applications in drug discovery and crop protection agent development.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates with antifungal, antibacterial, or antiviral properties.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides, leveraging the bioactivity of the triazole-thiol core.
• Ligand in Coordination Chemistry: Serves as a versatile ligand for metal complexes in catalysis and material science research due to its sulfur and nitrogen donor atoms.
• Polymer Additive Precursor: Investigated for the development of stabilizers, antioxidants, or curing agents for specialty polymers and resins.
• Chemical Research & Development: A fundamental reagent in academic and industrial labs for exploring new heterocyclic chemistry and reaction pathways.

Basic Information

Product Name	4-(2,4-Dimethylphenyl)-4H-1,2,4-Triazole-3-Thiol
CAS No.	66297-59-4
Molecular Formula	C10H11N3S
Molecular Weight	205.28 g/mol
Synonyms	4-(2,4-Dimethylphenyl)-1,2,4-triazole-3-thiol; 4-(2,4-Dimethylphenyl)-4H-1,2,4-triazole-3-thione; 3-Mercapto-4-(2,4-dimethylphenyl)-1,2,4-triazole; 1,2,4-Triazole-3-thiol, 4-(2,4-dimethylphenyl)-; 66297-59-4; 4-(2,4-Dimethylphenyl)-1H-1,2,4-triazole-3-thiol (tautomer)
EINECS	Contact for details

Quality Control

Our 4-(2,4-Dimethylphenyl)-4H-1,2,4-Triazole-3-Thiol is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Custom purity grades and analytical packages are available to meet specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This compound is easily oxidized; for long-term storage, consider an inert atmosphere (e.g., nitrogen or argon). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.