Description

Phenylthiohydantoin α-Aminobutyric Acid is a specialized derivative of α-aminobutyric acid, a non-proteinogenic amino acid, modified with a phenylthiohydantoin moiety. This compound is of significant value in advanced biochemical research and pharmaceutical development, particularly in peptide sequencing and proteomics studies. It is primarily utilized by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in synthesizing novel bioactive molecules or analytical standards.

Application

• Biochemical Research Reagent: Used as a key intermediate or reference standard in peptide and protein sequencing methodologies, particularly Edman degradation and related techniques.
• Pharmaceutical Intermediate: Serves as a building block in the synthesis of more complex molecules with potential pharmacological activity.
• Proteomics & Analytical Chemistry: Employed in the development and calibration of analytical methods for amino acid and peptide analysis via HPLC, LC-MS, or capillary electrophoresis.
• Academic Research: Utilized in university and institutional labs for studying amino acid chemistry, modification reactions, and enzyme-substrate interactions.
• Fine Chemical Synthesis: Acts as a precursor for the preparation of specialized derivatives, conjugates, or labeled compounds for diagnostic or research purposes.

Basic Information

Product Name	Phenylthiohydantoin α-Aminobutyric Acid
CAS No.	66256-32-4
Molecular Formula	C₁₁H₁₂N₂O₂S
Molecular Weight	236.29 g/mol
Synonyms	2-Amino-4-(phenylthiohydantoin)butanoic acid; PTH-Abu; PTH-α-Aminobutyric Acid; (RS)-2-Amino-4-(3-phenyl-2-thioxo-4-imidazolidinyl)butanoic acid; 4-(3-Phenyl-2-thioxo-4-imidazolidinyl)-2-aminobutanoic acid; α-Aminobutyric acid phenylthiohydantoin derivative; Phenyl-2-thiohydantoin derivative of 2-aminobutanoic acid
EINECS	Contact for details

Quality Control

Our Phenylthiohydantoin α-Aminobutyric Acid is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to minimize exposure to atmospheric moisture. For long-term storage, consider using a desiccator.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.