Description

4-(1-Hydroxy-2-Methylamino-Ethyl)Benzene-1,2-Diol Hydrochloride is a high-purity synthetic intermediate of significant importance in advanced pharmaceutical research and development. This compound serves as a critical precursor in the synthesis of complex active pharmaceutical ingredients (APIs), particularly those targeting adrenergic pathways. It is essential for manufacturers and research institutions engaged in the development of cardiovascular and neurological therapeutics, where precise chemical structure and purity are paramount for efficacy and safety.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of adrenergic receptor agonists and related APIs.
• Biochemical Research: Used as a reference standard or reagent in studies of catecholamine metabolism and receptor binding assays.
• Preclinical Development: Employed in the formulation and testing of novel drug candidates during early-stage R&D.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP production of specialty pharmaceuticals.
• Analytical Standard: Serves as a high-purity calibrant in HPLC and LC-MS methods for quality control in pharmaceutical labs.

Basic Information

Product Name	4-(1-Hydroxy-2-Methylamino-Ethyl)Benzene-1,2-Diol Hydrochloride
CAS No.	66240-90-2
Molecular Formula	C10H16ClNO3
Molecular Weight	233.69 g/mol
Synonyms	N-Methyldopamine Hydrochloride; 3,4-Dihydroxy-N-methylphenethylamine Hydrochloride; 2-(3,4-Dihydroxyphenyl)-N-methylethan-1-amine Hydrochloride; N-Methyl-3,4-dihydroxyphenethylamine HCl; N-Methyl dopamine HCl; α-Methylamino-3,4-dihydroxybenzyl alcohol hydrochloride; 4-(1-Hydroxy-2-(methylamino)ethyl)-1,2-benzenediol hydrochloride
EINECS	Contact for details

Quality Control

Our 4-(1-Hydroxy-2-Methylamino-Ethyl)Benzene-1,2-Diol Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and easily oxidized nature, the product should be handled under an inert atmosphere when possible and the container kept sealed to minimize exposure to moisture and air.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.