Description

Benzene, 2-Bromo-4-Chloro-1-(Chloromethyl)- is a halogenated benzene derivative of significant interest in advanced organic synthesis. This compound serves as a versatile and critical building block for the construction of complex molecular architectures, particularly in pharmaceutical and agrochemical research. Its unique substitution pattern makes it an essential intermediate for scientists and process chemists developing active ingredients and specialty chemicals.

Application

This multi-functional halogenated intermediate is employed in various high-value synthetic pathways. Key application areas include:

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those containing complex halogenated aromatic systems.
• Agrochemical Synthesis: Used in the research and development of herbicides, fungicides, and insecticides where its halogen atoms provide specific reactivity and bioactivity.
• Ligand and Catalyst Development: Acts as a starting material for creating specialized ligands used in metal-catalyzed cross-coupling reactions and other catalytic processes.
• Material Science Research: Employed in the synthesis of monomers or functional units for advanced polymers and organic electronic materials.
• Chemical Library Synthesis: A valuable scaffold for generating diverse compound libraries in medicinal chemistry for high-throughput screening.

Basic Information

Product Name	Benzene, 2-Bromo-4-Chloro-1-(Chloromethyl)-
CAS No.	66192-23-2
Molecular Formula	C7H5BrCl2
Molecular Weight	239.93 g/mol
Synonyms	1-(Chloromethyl)-2-bromo-4-chlorobenzene; 2-Bromo-4-chloro-1-(chloromethyl)benzene; 2-Bromo-4-chloro-α-chlorotoluene; 2-Bromo-4-chlorobenzyl chloride; alpha,2-Dibromo-4-chlorotoluene; Benzyl chloride, 2-bromo-4-chloro-; (2-Bromo-4-chlorophenyl)methyl chloride
EINECS	Contact for details

Quality Control

Our Benzene, 2-Bromo-4-Chloro-1-(Chloromethyl)- is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is analyzed using advanced chromatographic and spectroscopic techniques. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.