Description

Trifluoromethanesulfonic Acid-D is the deuterated isotopologue of trifluoromethanesulfonic acid, a superacid of exceptional strength and utility. This compound matters for its role as a powerful deuterated acid catalyst and reagent in advanced synthetic chemistry, offering unique properties for mechanistic studies and specialized synthesis. It is needed by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries, particularly for applications involving acid-catalyzed reactions where deuterium labeling is critical for NMR spectroscopy, kinetic isotope effect studies, or the synthesis of deuterated compounds.

Application

• Deuterated Acid Catalyst: Used as a superacid catalyst in deuterated solvent systems for organic synthesis, including Friedel-Crafts alkylation and acylation, esterification, and polymerization reactions.
• NMR Spectroscopy & Mechanistic Studies: Essential for probing reaction mechanisms and conducting kinetic isotope effect (KIE) studies due to the deuterium label, providing insights into proton transfer pathways.
• Deuteration Reagent: Employed for the specific introduction of deuterium atoms into organic molecules, a key step in the synthesis of deuterated active pharmaceutical ingredients (APIs) and other labeled compounds.
• Electrolyte Component: Investigated for use in specialized electrochemical applications and battery research where deuterated acidic media are required.
• Polymerization Initiator: Acts as a strong initiator for cationic polymerization of olefins and other monomers in deuterated form for advanced polymer research.
• Reagent in Organometallic Chemistry: Utilized for generating deuterated metal triflate complexes and as a strong acid in deuterium-labeled organometallic reactions.

Basic Information

Product Name	Trifluoromethanesulfonic Acid-D
CAS No.	66178-41-4
Molecular Formula	CF3SO3D
Molecular Weight	151.09 g/mol (for CF3SO3D)
Synonyms	Deuterated Triflic Acid; Trifluoromethanesulfonic Acid-d; Perfluoromethanesulfonic Acid-D; Triflic Acid-D; TfOD; Trifluoromethanesulfonic Acid Deuterated; Deuterio Trifluoromethanesulfonate; (Trideutero)Trifluoromethanesulfonic Acid
EINECS	Contact for details

Quality Control

Our Trifluoromethanesulfonic Acid-D is produced and handled under strict quality protocols to ensure high isotopic purity and chemical integrity, essential for sensitive research applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing key parameters such as isotopic purity (D atom %), chemical purity, and impurity profiles. We adhere to relevant industry standards for fine chemicals and can provide material tailored to specific research or GMP-grade requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area. Due to its nature as a strong acid/organic solvent, it should be kept separate from incompatible materials such as bases and reactive metals. For long-term stability, storage under an inert atmosphere (e.g., argon or nitrogen) is recommended to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Isotopic Purity (D atom %)	≥ 98%
Assay (Titration)	≥ 98%
Water Content (KF)	≤ 0.5%
NMR Purity	Conforms

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.