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2,3-Dihydro-1-Benzofuran-2-Ylmethanol CAS NO 66158-96-1


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CAS No.:66158-96-1

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2,3-Dihydro-1-Benzofuran-2-Ylmethanol is a versatile benzofuran derivative, a key chiral building block in advanced organic synthesis. Its value lies in its functionalized structure, which serves as a crucial intermediate for constructing complex molecules with high stereochemical control. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and novel chemical entities.

Application

  • Pharmaceutical Intermediate: A critical chiral synthon for the development of active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and cardiovascular drug candidates.
  • Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging the benzofuran scaffold for biological activity.
  • Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
  • Material Science Research: Employed in the synthesis of organic electronic materials and novel polymers due to its fused aromatic system.
  • Fine Chemical Production: Acts as a building block for flavors, fragrances, and other high-value specialty chemicals.
  • Academic & Industrial R&D: A valuable reagent for methodological development and exploring new chemical spaces in synthetic organic chemistry.

Basic Information

Product Name 2,3-Dihydro-1-Benzofuran-2-Ylmethanol
CAS No. 66158-96-1
Molecular Formula C10H12O2
Molecular Weight 164.20 g/mol
Synonyms 2-(Hydroxymethyl)-2,3-dihydro-1-benzofuran; 2,3-Dihydrobenzofuran-2-methanol; 2-Benzofuranmethanol, 2,3-dihydro-; (2,3-Dihydrobenzofuran-2-yl)methanol; 2-(Hydroxymethyl)-2,3-dihydrobenzofuran; Dihydrobenzofuran-2-ylmethanol
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Quality Control

Our 2,3-Dihydro-1-Benzofuran-2-Ylmethanol is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) with detailed chromatographic data (HPLC/GC) are provided to guarantee reproducible quality and performance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its sensitivity, it is recommended to store under an inert atmosphere for long-term preservation to minimize oxidation.

Specification

Item Specification
Appearance Colorless to pale yellow liquid or low-melting solid
Identification (IR) Conforms to structure
Purity (HPLC/GC) ≥ 97.0%
Chiral Purity (Chiral HPLC) ≥ 98.0% ee (enantiomeric excess)
Water Content (KF) ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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