Description

Ethyl Nicotinate-D4 is a deuterated derivative of ethyl nicotinate, a stable isotope-labeled compound where four hydrogen atoms are replaced by deuterium. This high-purity labeled standard is essential for ensuring accuracy and reliability in quantitative analytical methods, particularly mass spectrometry. It is primarily used by researchers and quality control laboratories in the pharmaceutical, agrochemical, and analytical chemistry industries for method development, validation, and as an internal standard.

Application

• Internal Standard for Quantitative Analysis: Serves as a critical reference compound in LC-MS and GC-MS for the precise quantification of ethyl nicotinate and related compounds in complex matrices.
• Pharmaceutical Research & Metabolism Studies: Used in pharmacokinetic, pharmacodynamic, and drug metabolism studies to track and quantify the parent compound and its metabolites.
• Analytical Method Development & Validation: Essential for developing and validating robust, sensitive, and specific analytical methods in compliance with regulatory guidelines (e.g., ICH, FDA).
• Isotope Dilution Mass Spectrometry (IDMS): Employed in high-accuracy IDMS techniques to minimize matrix effects and improve measurement precision.
• Chemical Reference Material: Acts as a certified reference material (CRM) or high-purity standard for instrument calibration and quality assurance programs.
• Agrochemical Analysis: Utilized in the analysis of pesticide formulations and environmental fate studies where nicotinate esters are relevant.

Basic Information

Product Name	Ethyl Nicotinate-D4
CAS No.	66148-16-1
Molecular Formula	C8D4H5NO2
Molecular Weight	167.18 g/mol
Synonyms	Ethyl Pyridine-3-carboxylate-D4; Deutero Ethyl Nicotinate; Nicotinic Acid Ethyl Ester-D4; 3-Carbethoxy-D4-pyridine; Ethyl 3-Pyridinecarboxylate-D4; Ethyl Niacin-D4; Ethyl Nicotinate (tetradeutero); 3-Pyridinecarboxylic Acid, Ethyl-d4 Ester
EINECS	Contact for details

Quality Control

Our Ethyl Nicotinate-D4 is manufactured under strict quality control protocols to ensure the highest isotopic purity and chemical integrity. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as isotopic enrichment (D-atom %), chemical purity (by HPLC), and identity confirmation (by NMR and MS). We adhere to relevant industry standards for stable isotope-labeled compounds to guarantee consistency and reliability for your critical research and analytical applications.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. The product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥98.0%
Isotopic Purity (D-atom %)	≥98.0%
Isotopic Enrichment (MS)	≥98.0% (D4)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.