Description

3-Bromopyridine-D4 is a deuterated analog of 3-bromopyridine, where four hydrogen atoms are replaced with deuterium, a stable isotope of hydrogen. This isotopic labeling is critical for creating internal standards in mass spectrometry and for mechanistic studies in pharmaceutical and agrochemical research, enhancing analytical precision and traceability. It is an essential building block for researchers and manufacturers in the fields of analytical chemistry, drug discovery, and advanced material science.

Application

• Internal Standard for Quantitative Analysis: Used as a deuterated internal standard in LC-MS and GC-MS for the accurate quantification of 3-bromopyridine and related compounds in complex matrices.
• Pharmaceutical Research: Serves as a labeled precursor or intermediate in the synthesis of deuterated drug candidates for pharmacokinetic and metabolic studies.
• Mechanistic Studies: Employed in reaction mechanism elucidation and isotope effect studies due to the kinetic isotope effect (KIE) of deuterium.
• Agrochemical Development: Used in the synthesis of labeled agrochemicals for environmental fate and residue analysis studies.
• NMR Spectroscopy: Acts as a useful solvent or reference compound in nuclear magnetic resonance spectroscopy.
• Material Science: A potential building block for creating deuterated organic electronic materials or liquid crystals.

Basic Information

Item	Details
Product Name	3-Bromopyridine-D4
CAS No.	66148-14-9
Molecular Formula	C5D4BrN
Molecular Weight	162.01 g/mol (approx.)
Synonyms	3-Bromo-d4-pyridine; Pyridine-d4, 3-bromo-; Deuterated 3-Bromopyridine; 3-Bromopyridine (phenyl-D4); 3-Bromopyridine-d4; [2H4]-3-Bromopyridine; 3-Bromopyridine (tetradeutero); 3-Bromopyridine (ring-D4)
EINECS	Contact for details

Quality Control

Our 3-Bromopyridine-D4 is produced under strict quality protocols to ensure high isotopic purity and chemical integrity, essential for reliable analytical and synthetic applications. Each batch undergoes comprehensive analysis, including NMR, HPLC, and mass spectrometry, to confirm deuterium incorporation and chemical purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong acids and incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain isotopic purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-content)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.