Description

Talmetoprim is a synthetic antibacterial agent belonging to the diaminopyrimidine class, structurally related to trimethoprim. This compound is valued for its role as a potent inhibitor of bacterial dihydrofolate reductase (DHFR), which is critical for nucleic acid synthesis. It is primarily utilized in the development of veterinary and pharmaceutical formulations to combat bacterial infections. Professionals in the animal health, pharmaceutical research, and fine chemical synthesis sectors require this high-purity intermediate for developing effective antimicrobial treatments.

Application

• Veterinary Pharmaceutical Intermediate: A key active pharmaceutical ingredient (API) or precursor in formulations for treating bacterial infections in livestock and companion animals.
• Antibacterial Synergist: Used in combination with sulfonamides to create potentiated sulfa drugs, enhancing efficacy against a broad spectrum of pathogens.
• Research & Development: Serves as a critical reference standard and building block in microbiological and pharmacological research for novel DHFR inhibitors.
• Fine Chemical Synthesis: Employed as a specialized intermediate in the custom synthesis of more complex antimicrobial agents and prodrugs.
• Aquaculture Treatments: Investigated for use in medicated feeds to control bacterial diseases in farmed fish and shellfish.
• Poultry Health Management: Incorporated into preventative and therapeutic regimens for respiratory and enteric diseases in poultry.

Basic Information

Product Name	Talmetoprim
CAS No.	66093-35-4
Molecular Formula	C₁₃H₁₆N₄O₂
Molecular Weight	260.29 g/mol
Synonyms	2,4-Diamino-5-(3,4,5-trimethoxybenzyl)pyrimidine; 5-[(3,4,5-Trimethoxyphenyl)methyl]-2,4-pyrimidinediamine; TMP; Talmetoprimum; Diaminopyrimidine antibacterial
EINECS	Contact for details

Quality Control

Our Talmetoprim is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. The product undergoes comprehensive analytical testing, including HPLC for assay and related substances, residual solvent analysis, and identification by spectroscopic methods. A Certificate of Analysis (COA) detailing all test results is provided with each shipment to guarantee compliance with your specifications and relevant industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.