Description

(S)-(+)-(1-Aminoethyl)Phosphonic Acid CAS NO 66068-76-6 is a high-purity, single-enantiomer organophosphorus compound characterized by its chiral amino acid-like structure. This compound matters as a versatile chiral building block and ligand, essential for synthesizing enantiomerically pure pharmaceuticals and creating selective catalysts. It is needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for applications in asymmetric synthesis and as a precursor to biologically active molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of enantiomerically pure drugs, particularly those targeting bone metabolism or requiring phosphonate moieties.
• Asymmetric Catalyst Ligand: Serves as a precursor for chiral phosphine or phosphonate ligands used in homogeneous catalysis, such as hydrogenation or cross-coupling reactions.
• Agrochemical Research: Used in the synthesis of novel, chiral herbicides, plant growth regulators, or fungicides with potentially improved activity and selectivity.
• Biomimetic Chemistry: Acts as a non-hydrolyzable analog of phosphoserine or phosphothreonine for studying enzyme mechanisms, signal transduction, and protein interactions.
• Material Science: Employed in the surface functionalization of materials or as a monomer for specialty polymers where chirality and phosphonic acid groups impart specific properties.
• Analytical Chemistry: Utilized as a chiral selector or resolving agent in chromatography for the separation of enantiomers.

Basic Information

Product Name	(S)-(+)-(1-Aminoethyl)Phosphonic Acid
CAS No.	66068-76-6
Molecular Formula	C₂H₈NO₃P
Molecular Weight	125.06 g/mol
Synonyms	(S)-1-Aminoethylphosphonic Acid; (S)-AEP; (S)-(+)-1-Aminoethanephosphonic Acid; L-1-Aminoethylphosphonic Acid; (S)-Aminoethylphosphonate; Phosphonoglycine; (S)-Phosphonoalanine; (1S)-1-Aminoethylphosphonic Acid
EINECS	Contact for details

Quality Control

Our (S)-(+)-(1-Aminoethyl)Phosphonic Acid is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure compliance with high-purity standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles is provided with every shipment to guarantee reliable and consistent material for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.