Description

4-Bromo-2,3-Dihydro-1H-Indene-1-Carboxylic Acid is a high-purity, versatile brominated indane derivative that serves as a critical pharmaceutical intermediate and organic synthesis building block. Its unique fused-ring structure with both carboxylic acid and bromine functional groups makes it an essential precursor for constructing complex molecules in medicinal chemistry. This compound is primarily utilized by R&D laboratories and fine chemical manufacturers engaged in the development of active pharmaceutical ingredients (APIs) and advanced materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Organic Synthesis Reagent: Used in cross-coupling reactions (e.g., Suzuki, Heck) and nucleophilic substitution reactions to introduce the indane scaffold.
• Agrochemical Research: Intermediate in the development of new generation herbicides and plant growth regulators.
• Material Science: Precursor for functionalized polymers and liquid crystalline materials.
• Chemical Biology: Useful for creating molecular probes and enzyme inhibitors due to its rigid, hydrophobic structure.

Basic Information

Product Name	4-Bromo-2,3-Dihydro-1H-Indene-1-Carboxylic Acid
CAS No.	66041-35-8
Molecular Formula	C10H9BrO2
Molecular Weight	241.08 g/mol
Synonyms	4-Bromoindane-1-carboxylic Acid; 1H-Indene-1-carboxylic acid, 4-bromo-2,3-dihydro-; 4-Bromo-2,3-dihydro-1H-indene-1-carboxylate; 4-Bromoindan-1-carboxylic Acid; 4-Bromo-1-indancarboxylic Acid; 4-Bromohydrindene-1-carboxylic Acid; 4-Bromo-2,3-dihydro-1H-inden-1-carboxylic Acid; 4-Bromo-1-carboxyindane
EINECS	Contact for details

Quality Control

Our 4-Bromo-2,3-Dihydro-1H-Indene-1-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high chemical purity and structural identity. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and organic solvents. The compound is light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.