Description

1-[6,7-Dimethoxy-1-(4-Nitro-Phenyl)-3,4-Dihydro-1H-Isoquinolin-2-Yl]-Ethanone is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel bioactive molecules. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to develop new isoquinoline-based compounds with optimized biological activity.
• Active Pharmaceutical Ingredient (API) Development: Serves as a precursor in multi-step synthetic routes for complex APIs.
• Biochemical Research: Employed as a tool compound in biochemical assays to study enzyme inhibition or receptor binding.
• Fine Chemical Synthesis: Utilized in custom synthesis and contract manufacturing for specialized chemical entities.

Basic Information

Product Name	1-[6,7-Dimethoxy-1-(4-Nitro-Phenyl)-3,4-Dihydro-1H-Isoquinolin-2-Yl]-Ethanone
CAS No.	66040-42-4
Molecular Formula	C19H18N2O5
Molecular Weight	354.36 g/mol
Synonyms	1-[6,7-Dimethoxy-1-(4-nitrophenyl)-3,4-dihydro-1H-isoquinolin-2-yl]ethanone; 2-Acetyl-1-(4-nitrophenyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline; Ethanone, 1-[6,7-dimethoxy-1-(4-nitrophenyl)-3,4-dihydro-1H-isoquinolin-2-yl]-; 1-(4-Nitrophenyl)-6,7-dimethoxy-2-acetyl-1,2,3,4-tetrahydroisoquinoline; 66040-42-4; Tetrahydroisoquinoline derivative, acetyl nitro dimethoxy phenyl substituted
EINECS	Contact for details

Quality Control

Our 1-[6,7-Dimethoxy-1-(4-Nitro-Phenyl)-3,4-Dihydro-1H-Isoquinolin-2-Yl]-Ethanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Keep the container sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.