Description

1,1-Bis(Trimethylsilyloxy)-2-Trimethylsilylethene is a specialized organosilicon reagent featuring three trimethylsilyl (TMS) protecting groups. This compound is highly valued in synthetic organic chemistry for its role as a versatile precursor and protecting group agent for carbonyl compounds. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecular architectures.

Application

• Synthetic Intermediate in the production of complex organic molecules, particularly in multi-step pharmaceutical synthesis.
• Carbonyl Protection reagent for ketones and aldehydes, enabling selective reactions at other functional groups.
• Precursor for Silyl Enol Ethers, which are crucial intermediates for regioselective alkylation, acylation, and aldol reactions.
• Building Block in materials science for the synthesis of silicon-containing polymers or hybrid materials.
• Research & Development tool in academic and industrial laboratories for methodology development and exploratory synthesis.
• Process Chemistry for scaling up the manufacture of active pharmaceutical ingredients (APIs) and fine chemicals.

Basic Information

Product Name	1,1-Bis(Trimethylsilyloxy)-2-Trimethylsilylethene
CAS No.	65946-59-0
Molecular Formula	C11H28O2Si3
Molecular Weight	276.60 g/mol
Synonyms	1,1-Bis(trimethylsiloxy)-2-(trimethylsilyl)ethene; 2-(Trimethylsilyl)-1,1-bis(trimethylsiloxy)ethene; 1,1,2-Tris(trimethylsiloxy)ethene; Tris(trimethylsilyl) Ketene Acetal; TMS Ketene Acetal; Bis(trimethylsilyl) Ketene O,O-Acetal; Ketene Bis(trimethylsilyl) Acetal; EINECS 266-059-1
EINECS	266-059-1

Quality Control

Our 1,1-Bis(Trimethylsilyloxy)-2-Trimethylsilylethene is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for demanding synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality management system supports compliance with cGMP and ISO standards for research and commercial-scale supply.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC or NMR)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.