Description

Trimethylsilylketene Ethyl Trimethylsilyl Acetal (Mixture Of Isomers) is a versatile organosilicon reagent primarily used as a key synthon in advanced organic synthesis. This compound matters for its ability to act as a protected ketene equivalent, facilitating the introduction of functionalized acetyl units under mild conditions. It is essential for researchers and process chemists in the pharmaceutical, agrochemical, and specialty chemical industries developing novel active ingredients and complex molecules.

Application

• Pharmaceutical Intermediate Synthesis: A crucial building block for constructing β-lactam rings, quinolone antibiotics, and other heterocyclic cores in API development.
• Agrochemical Production: Used in the synthesis of advanced herbicides, fungicides, and plant growth regulators requiring specific acetyl or carboxylate functionalities.
• Material Science Research: Serves as a precursor for modifying polymer backbones or creating novel silicon-containing monomers with tailored properties.
• Natural Product & Fine Chemical Synthesis: Enables stereoselective chain elongation and the installation of complex ester or ketone groups in target molecules.
• Process Chemistry & Scale-up: Valued for its reactivity profile in multi-step synthesis, offering efficient routes for kilogram-to-ton scale production.

Basic Information

Product Name	Trimethylsilylketene Ethyl Trimethylsilyl Acetal (Mixture Of Isomers)
CAS No.	65946-56-7
Molecular Formula	C10H22O2Si2
Molecular Weight	230.45 g/mol
Synonyms	Ethyl (Trimethylsilyl)ketene Trimethylsilyl Acetal; (Ethoxyvinyloxy)trimethylsilane, (Trimethylsilyl)ketene Acetal; 1-Ethoxy-1-[(trimethylsilyl)oxy]-2-(trimethylsilyl)ethene; Ketene Ethyl Trimethylsilyl Acetal, Trimethylsilylated; TMS-Ketene Ethyl TMS Acetal; Silyl Ketene Acetal Derivative
EINECS	Contact for details

Quality Control

Our Trimethylsilylketene Ethyl Trimethylsilyl Acetal is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, NMR, and Karl Fischer titration, to ensure high purity and consistency. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (argon or nitrogen) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 95.0% (Isomeric Mixture)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.