Description

3-Bromopyridine-2-Thiol is a versatile sulfur- and nitrogen-containing heterocyclic building block with significant synthetic utility. Its bifunctional structure, featuring both a reactive bromine atom and a thiol group, makes it a critical intermediate for constructing complex molecules in advanced research and development. This compound is primarily sought after by pharmaceutical, agrochemical, and material science industries for applications in medicinal chemistry, ligand synthesis, and the development of functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting neurological disorders and infectious diseases.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides due to its heterocyclic core.
• Ligand Precursor: Serves as a starting material for the preparation of chelating ligands in coordination chemistry and catalysis.
• Material Science: Employed in the research and development of organic semiconductors, conductive polymers, and metal-organic frameworks (MOFs).
• Chemical Research: A valuable reagent for heterocyclic chemistry, facilitating Suzuki, Buchwald-Hartwig, and other cross-coupling reactions.
• Bioconjugation: The thiol group allows for use in bioconjugation techniques for labeling proteins and other biomolecules.

Basic Information

Product Name	3-Bromopyridine-2-Thiol
CAS No.	65938-86-5
Molecular Formula	C5H4BrNS
Molecular Weight	190.06 g/mol
Synonyms	2-Mercapto-3-bromopyridine; 3-Bromo-2-pyridinethiol; 3-Bromo-2-mercaptopyridine; 2-Pyridinethiol, 3-bromo-; 3-Bromopyridine-2-thione (tautomer); 3-Bromo-2(1H)-pyridinethione
EINECS	Contact for details

Quality Control

Our 3-Bromopyridine-2-Thiol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C) under an inert atmosphere (e.g., nitrogen or argon) to prevent oxidation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.