Description

5-Methylindole-3-Acetonitrile is a versatile indole-based nitrile compound that serves as a critical synthetic intermediate in advanced organic chemistry. Its value lies in its functionalized indole core, which provides a strategic building block for constructing complex molecules with biological relevance. This high-purity intermediate is essential for research and development chemists in the pharmaceutical, agrochemical, and fine chemical sectors seeking to develop novel active compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting serotonin-related pathways, neurological disorders, and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the research and development of new generation pesticides and plant growth regulators that leverage the indole scaffold.
• Fine Chemical Building Block: Employed in the preparation of complex dyes, pigments, and advanced materials requiring functionalized heterocyclic structures.
• Biochemical Research: Serves as a standard or reagent in studies involving tryptophan metabolism and the synthesis of melatonin analogs.
• Organic Synthesis: Utilized in various name reactions and as a starting material for generating libraries of indole derivatives for screening purposes.

Basic Information

Product Name	5-Methylindole-3-Acetonitrile
CAS No.	65881-14-3
Molecular Formula	C11H10N2
Molecular Weight	170.21 g/mol
Synonyms	5-Methyl-1H-indole-3-acetonitrile; (5-Methyl-1H-indol-3-yl)acetonitrile; 3-(Cyanomethyl)-5-methylindole; 5-Methylindolyl-3-acetonitrile; 5-Methyl-3-indoleacetonitrile; 2-(5-Methyl-1H-indol-3-yl)acetonitrile
EINECS	Contact for details

Quality Control

Our 5-Methylindole-3-Acetonitrile is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and impurity profiling, to meet the stringent requirements of our global clientele in research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and conformity to agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.