Description

Oxazepam-D5 is a deuterated internal standard of the benzodiazepine anxiolytic, Oxazepam, specifically designed for analytical applications. This stable isotope-labeled compound is essential for ensuring the accuracy and precision of quantitative analysis in complex matrices. It is a critical tool for researchers and quality control laboratories in the pharmaceutical, forensic toxicology, and clinical research sectors who require reliable reference materials for method development and validation.

Application

• Internal Standard for LC-MS/MS and GC-MS: Primary application for the precise quantification of Oxazepam in pharmacokinetic, bioequivalence, and forensic studies.
• Pharmaceutical Research & Development: Used in drug metabolism and pharmacokinetics (DMPK) studies to track the parent drug and its metabolites.
• Forensic Toxicology: Essential for the accurate analysis of benzodiazepines in biological samples for legal and medical purposes.
• Clinical Research: Supports studies investigating drug efficacy, safety profiles, and patient compliance.
• Method Development & Validation: Serves as a critical reference standard to establish and verify analytical methods according to ICH and other regulatory guidelines.
• Quality Control in Manufacturing: Used to monitor the purity and consistency of Oxazepam in active pharmaceutical ingredient (API) production.

Basic Information

Product Name	Oxazepam-D5
CAS No.	65854-78-6
Molecular Formula	C15H6D5ClN2O2
Molecular Weight	291.75 g/mol
Synonyms	7-Chloro-1,3-dihydro-3-hydroxy-5-phenyl-2H-1,4-benzodiazepin-2-one-d5; Oxazepam (phenyl-d5); Oxazepam-d5 (Major); 7-Chloro-2,3-dihydro-2-oxo-5-phenyl-1H-1,4-benzodiazepine-3-ol-d5; Serax-d5; Adumbran-d5; Seresta-d5
EINECS	Contact for details

Quality Control

Our Oxazepam-D5 is manufactured under strict quality systems to ensure the highest standards of isotopic purity and chemical identity required for analytical applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing results from advanced spectroscopic and chromatographic tests, including NMR, HPLC, and MS. We support compliance with GMP/GLP guidelines for reference standards.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term stability, consider storage at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (NMR/MS)	≥ 98.0 atom % D
Chemical Purity	≥ 95.0%
Residual Solvents (GC)	Complies with ICH limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.