Description

5-Chloro-4-Methyl-2-Thiophenecarboxaldehyde is a versatile heterocyclic building block featuring both aldehyde and chloro functionalities on a substituted thiophene core. This compound is critical for the synthesis of complex molecules, particularly in pharmaceutical research and advanced material science. It is primarily sought after by R&D chemists and process development scientists in the agrochemical, pharmaceutical, and specialty chemical industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in antiviral, antibacterial, and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides, leveraging its reactive aldehyde group for further derivatization.
• Material Science Precursor: Serves as a building block for organic semiconductors, conductive polymers, and liquid crystals due to the electron-rich thiophene ring.
• Chemical Research (R&D): Employed in academic and industrial laboratories for heterocyclic chemistry studies, method development, and library synthesis for high-throughput screening.
• Dye and Pigment Manufacturing: Acts as an intermediate in the synthesis of specialized dyes and organic pigments where the thiophene moiety imparts specific color and stability properties.
• Ligand and Catalyst Development: Utilized to create novel ligands for metal catalysis and organocatalysts, exploiting the coordination potential of the sulfur and aldehyde oxygen.

Basic Information

Product Name	5-Chloro-4-Methyl-2-Thiophenecarboxaldehyde
CAS No.	65782-04-9
Molecular Formula	C7H5ClOS
Molecular Weight	172.63 g/mol
Synonyms	5-Chloro-4-methylthiophene-2-carboxaldehyde; 2-Formyl-5-chloro-4-methylthiophene; 5-Chloro-4-methyl-2-thiophenecarbaldehyde; 4-Methyl-5-chlorothiophene-2-carboxaldehyde; 5-Chloro-4-methyl-2-thienylcarboxaldehyde; 2-Thiophenecarboxaldehyde, 5-chloro-4-methyl-; 5-Chloro-4-methylthiophene-2-carbaldehyde
EINECS	Contact for details

Quality Control

Our 5-Chloro-4-Methyl-2-Thiophenecarboxaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, GC for residual solvents, and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) detailing all specifications are available upon request, and we support compliance with relevant regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized and should be handled and stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.