Description

2,4-Thiophenedicarboxaldehyde, 5-Amino- (9Ci) is a heterocyclic organic compound featuring both amino and aldehyde functional groups on a thiophene backbone. This unique bifunctional structure makes it a valuable and versatile advanced pharmaceutical intermediate and a key building block in organic synthesis. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for compounds targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic core for bioactivity.
• Ligand and Catalyst Development: Acts as a starting material for creating specialized ligands and catalysts used in asymmetric synthesis and metal-organic frameworks (MOFs).
• Functional Material Research: Employed in the development of organic semiconductors, conductive polymers, and nonlinear optical (NLO) materials due to the electron-rich thiophene unit.
• Dye and Pigment Chemistry: Functions as a key intermediate for synthesizing specialized dyes and pigments with specific light-absorption properties.
• Cross-coupling Reactions: The amino and aldehyde groups provide handles for further functionalization via reactions like reductive amination, condensation, and palladium-catalyzed couplings.

Basic Information

Product Name	2,4-Thiophenedicarboxaldehyde, 5-Amino- (9Ci)
CAS No.	65762-95-0
Molecular Formula	C7H5NO2S
Molecular Weight	167.18 g/mol
Synonyms	5-Amino-2,4-thiophenedicarboxaldehyde; 5-Aminothiophene-2,4-dicarboxaldehyde; 2,4-Thiophenedicarboxaldehyde, 5-amino-; 5-Amino-2,4-diformylthiophene; Thiophene-2,4-dicarboxaldehyde, 5-amino-; 5-Aminothiophene-2,4-dialdehyde; 2,4-Diformyl-5-aminothiophene
EINECS	Contact for details

Quality Control

Our 2,4-Thiophenedicarboxaldehyde, 5-Amino- (9Ci) is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure high purity and consistent performance as a synthesis intermediate. Standard quality checks include identity confirmation (IR, NMR), purity assay (HPLC), and control of key impurities. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere). For long-term storage, consider packaging under an inert gas such as nitrogen or argon. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Yellow to brown powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0% (Area %)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.