Description

Apramycin Sulfate CAS NO 65710-07-8 is a water-soluble aminoglycoside antibiotic derived from *Streptomyces tenebrarius*. This compound is valued for its broad-spectrum activity against Gram-negative bacteria and specific efficacy against strains resistant to other aminoglycosides. It is a critical raw material for the veterinary pharmaceutical industry, primarily used in the formulation of animal health products.

Application

• Veterinary Pharmaceutical Ingredient: Primary use as an active pharmaceutical ingredient (API) in injectable solutions, premixes, and water-soluble powders for the treatment of bacterial infections in livestock, poultry, and swine.
• Animal Feed Additive: Incorporated into medicated feeds for growth promotion and disease prevention, particularly in intensive farming operations.
• Aquaculture: Used in the treatment of bacterial diseases in farmed fish and shrimp.
• Research & Development: Serves as a selective agent in microbiological research and as a reference standard in analytical laboratories for quality control testing.
• Veterinary Dermatology: Found in topical formulations for treating bacterial skin infections in companion animals.

Basic Information

Product Name	Apramycin Sulfate
CAS No.	65710-07-8
Molecular Formula	C21H41N5O11 • xH2SO4
Molecular Weight	539.6 g/mol (for base, excluding sulfate counterions)
Synonyms	Apramycin Sulphate; Nebramycin II; 4-O-(6-Amino-6-deoxy-α-D-glucopyranosyl)-6-O-(3-deoxy-4-C-methyl-3-methylamino-β-L-arabinopyranosyl)-2-deoxystreptamine sulfate; APR; Apramycin Sulfate Salt; Antibiotic APR; EL-857/820
EINECS	Contact for details

Quality Control

Our Apramycin Sulfate is manufactured under a GMP-compliant quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for potency, microbial limits testing, and residual solvent analysis, to ensure it meets stringent specifications for pharmaceutical use. A Certificate of Analysis (COA) documenting purity, identity, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a low-humidity environment to prevent degradation and clumping.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC, on dried basis)	≥ 95.0%
pH (1% solution)	5.0 - 7.0
Loss on Drying	≤ 5.0%
Residue on Ignition	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.