Description

4-[(1S)-3,4-Dihydro-6,7-Dimethoxy-1-Methylisoquinolin-2(1H)-Yl]Benzenamine is a high-purity chiral isoquinoline derivative, a critical building block in advanced organic synthesis. Its value lies in its role as a sophisticated intermediate for creating complex molecules with specific stereochemistry. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel therapeutic agents, including potential central nervous system (CNS) drugs and alkaloid-based medicines.
• Agrochemical Synthesis: Used in the production of advanced, targeted pesticides and herbicides where specific stereochemistry is crucial for efficacy and environmental safety.
• Chemical Research & Development: Serves as a valuable scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and the discovery of new bioactive compounds.
• Asymmetric Catalysis: Can be utilized as a precursor or ligand in the development of chiral catalysts for enantioselective synthesis.
• Reference Standard: Supplied as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	4-[(1S)-3,4-Dihydro-6,7-Dimethoxy-1-Methylisoquinolin-2(1H)-Yl]Benzenamine
CAS No.	65492-86-6
Molecular Formula	C₁₉H₂₂N₂O₂
Molecular Weight	310.39 g/mol
Synonyms	(S)-4-(6,7-Dimethoxy-1-methyl-1,2,3,4-tetrahydroisoquinolin-2-yl)aniline; (S)-2-(4-Aminophenyl)-6,7-dimethoxy-1-methyl-1,2,3,4-tetrahydroisoquinoline; 4-[(1S)-6,7-Dimethoxy-1-methyl-3,4-dihydro-1H-isoquinolin-2-yl]aniline; (S)-NSC 339579; (S)-Tetrahydropapaveroline derivative; (S)-THP derivative; (S)-1-Methyl-6,7-dimethoxy-2-(4-aminophenyl)-1,2,3,4-tetrahydroisoquinoline
EINECS	Contact for details

Quality Control

Our 4-[(1S)-3,4-Dihydro-6,7-Dimethoxy-1-Methylisoquinolin-2(1H)-Yl]Benzenamine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) detailing identity, purity, and chiral excess are provided with each shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.