Description

(1S)-6,7-Dimethoxy-1-Methyl-2-(1-Methylethyl)-1,2,3,4-Tetrahydroisoquinoline is a chiral tetrahydroisoquinoline derivative of significant interest in advanced organic synthesis. This compound serves as a critical chiral building block for the development of complex pharmaceutical molecules and bioactive alkaloids. It is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers engaged in the synthesis of potential drug candidates, particularly those targeting neurological and cardiovascular pathways.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of novel therapeutic agents, including potential anti-hypertensive and neuroactive compounds.
• Asymmetric Synthesis: Utilized as a chiral auxiliary or scaffold in stereoselective reactions to construct complex molecular architectures.
• Alkaloid Research: Serves as a core structural motif for the synthesis and study of tetrahydroisoquinoline-based natural products and their analogs.
• Chemical Biology: Used in the development of molecular probes and tool compounds for studying biological receptors and enzyme functions.
• Process Chemistry: Employed in route scouting and optimization for the scalable production of active pharmaceutical ingredients (APIs).
• Academic Research: A valuable reagent for universities and research institutions exploring new synthetic methodologies and medicinal chemistry.

Basic Information

Product Name	(1S)-6,7-Dimethoxy-1-Methyl-2-(1-Methylethyl)-1,2,3,4-Tetrahydroisoquinoline
CAS No.	65492-85-5
Molecular Formula	C15H23NO2
Molecular Weight	249.35 g/mol
Synonyms	(S)-6,7-Dimethoxy-1-methyl-2-isopropyl-1,2,3,4-tetrahydroisoquinoline; (1S)-1-Methyl-2-isopropyl-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline; (S)-1-Methyl-2-isopropyl-6,7-dimethoxytetrahydroisoquinoline; (S)-2-Isopropyl-1-methyl-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline; (S)-6,7-Dimethoxy-1-methyl-2-(propan-2-yl)-1,2,3,4-tetrahydroisoquinoline; (1S)-1-Methyl-2-(1-methylethyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline; (S)-Carnegine (enantiomer); (S)-Carnegine
EINECS	Contact for details

Quality Control

Our (1S)-6,7-Dimethoxy-1-Methyl-2-(1-Methylethyl)-1,2,3,4-Tetrahydroisoquinoline is produced under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure high chemical and chiral purity, meeting the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.