Description

2-Carboxyphenyl-1-(4-Chlorobenzoyl)-5-Methoxy-2-Methylindole-3-Acetate is a high-purity, non-steroidal anti-inflammatory drug (NSAID) intermediate with significant commercial and research value. This compound is critical for the synthesis of advanced pharmaceutical agents, particularly those targeting inflammation and pain. It is primarily required by pharmaceutical R&D laboratories, API (Active Pharmaceutical Ingredient) manufacturers, and fine chemical suppliers serving the global healthcare sector.

Application

• Key Intermediate in NSAID Synthesis: Serves as a crucial building block in the production of indole-based anti-inflammatory drugs.
• Pharmaceutical Research & Development: Used in medicinal chemistry for the discovery and optimization of new therapeutic candidates targeting COX enzymes.
• Active Pharmaceutical Ingredient (API) Manufacturing: Employed in the scaled-up synthesis of final drug substances under controlled GMP environments.
• Reference Standard: Provides a high-purity standard for analytical method development, validation, and quality control testing in regulatory submissions.
• Biochemical Studies: Utilized in pharmacological research to study inflammatory pathways and drug-receptor interactions.
• Fine Chemical Production: Supplied to chemical companies for further functionalization and creation of specialized derivative libraries.

Basic Information

Product Name	2-Carboxyphenyl-1-(4-Chlorobenzoyl)-5-Methoxy-2-Methylindole-3-Acetate
CAS No.	65474-39-7
Molecular Formula	C26H20ClNO6
Molecular Weight	477.89 g/mol
Synonyms	1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetic Acid 2-Carboxyphenyl Ester; Indomethacin Ester Derivative; 2-(1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl)acetic Acid 2-Carboxyphenyl Ester; 65474-39-7; 1H-Indole-3-acetic acid, 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-, 2-carboxyphenyl ester; Indomethacin carboxyphenyl ester; [1-(4-Chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]acetate 2-carboxyphenyl ester
EINECS	Contact for details

Quality Control

Our 2-Carboxyphenyl-1-(4-Chlorobenzoyl)-5-Methoxy-2-Methylindole-3-Acetate is manufactured under strict quality management systems to ensure batch-to-batch consistency and reliability for critical pharmaceutical applications. We provide comprehensive analytical documentation, including Certificates of Analysis (COA) with detailed chromatographic purity data, identity confirmation, and impurity profiles. Our quality commitment aligns with the standards expected for pharmaceutical intermediates, supporting our clients' regulatory and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials such as strong oxidizing agents, strong bases, and strong acids.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0% Any single unknown impurity ≤0.5%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.