Description

2-Amino-5-Isopropyl-Thiophene-3-Carboxylic Acid Ethyl Ester is a high-purity (97%) heterocyclic building block of significant importance in advanced organic synthesis. This compound serves as a critical intermediate for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and functional materials. It is primarily needed by research and development laboratories, pharmaceutical manufacturers, and fine chemical producers engaged in the synthesis of novel thiophene-based compounds.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and infectious diseases.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides that leverage the thiophene moiety for enhanced biological activity.
• Material Science: Serves as a precursor for organic semiconductors, conductive polymers, and nonlinear optical (NLO) materials due to its electron-rich thiophene core.
• Dye & Pigment Synthesis: Employed in the production of specialized dyes and pigments where the amino and ester functionalities allow for further chemical modifications.
• Academic & Contract Research: Essential for methodological development and exploratory chemistry in university and CRO (Contract Research Organization) settings.

Basic Information

Product Name	2-Amino-5-Isopropyl-Thiophene-3-Carboxylic Acid Ethyl Ester
CAS No.	65416-85-5
Molecular Formula	C11H17NO2S
Molecular Weight	227.32 g/mol
Synonyms	Ethyl 2-Amino-5-(1-methylethyl)thiophene-3-carboxylate; 2-Amino-5-isopropylthiophene-3-carboxylic acid ethyl ester; 5-Isopropyl-2-aminothiophene-3-carboxylic acid ethyl ester; Ethyl 5-isopropyl-2-aminothiophene-3-carboxylate; 3-Thiophenecarboxylic acid, 2-amino-5-(1-methylethyl)-, ethyl ester; AI3-52011; NSC 405124; Ethyl 2-amino-5-propan-2-ylthiophene-3-carboxylate
EINECS	Contact for details

Quality Control

Our 2-Amino-5-Isopropyl-Thiophene-3-Carboxylic Acid Ethyl Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced chromatographic and spectroscopic techniques. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect product stability and performance.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.