Description

Methyl 4-Acetoxythiophene-3-Carboxylate is a high-purity, functionalized thiophene derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its reactive ester and acetoxy groups, which enable efficient derivatization and incorporation into complex molecular architectures. It is primarily sought after by research institutions and industrial R&D teams in the pharmaceutical, agrochemical, and materials science sectors for developing novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in medicinal chemistry programs targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced crop protection agents and herbicides.
• Organic Electronic Materials: Serves as a precursor for conjugated polymers and small molecules used in organic light-emitting diodes (OLEDs) and organic photovoltaics (OPVs).
• Chemical Research: Employed in academic and industrial laboratories for method development and the synthesis of complex heterocyclic compounds.
• Ligand and Catalyst Development: Utilized to create novel ligands and organocatalysts for asymmetric synthesis.
• Specialty Polymer Monomer: Acts as a functional monomer for introducing thiophene units into specialty polymers with tailored properties.

Basic Information

Product Name	Methyl 4-Acetoxythiophene-3-Carboxylate
CAS No.	65369-31-5
Molecular Formula	C8H8O4S
Molecular Weight	200.21 g/mol
Synonyms	Methyl 4-acetyloxythiophene-3-carboxylate; 3-Thiophenecarboxylic acid, 4-(acetyloxy)-, methyl ester; 4-Acetoxythiophene-3-carboxylic acid methyl ester; Methyl 4-acetoxythiophene-3-carboxylate; 4-(Acetyloxy)thiophene-3-carboxylic Acid Methyl Ester; 3-Carbomethoxy-4-acetoxythiophene
EINECS	Contact for details

Quality Control

Our Methyl 4-Acetoxythiophene-3-Carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP principles where applicable to support our clients in regulated development pipelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. For long-term storage, consider inert gas purging to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.