Description

2-Amino-4-(4-Chloro-Phenyl)-Thiophene-3-Carboxylic Acid Ethyl Ester is a high-purity, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound matters because it serves as a critical intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, enabling the creation of complex molecular architectures. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing thiophene-based scaffolds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in therapeutic areas requiring thiophene cores.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its bioactive heterocyclic structure.
• Material Science Precursor: Serves as a monomer or precursor for functional polymers and organic electronic materials.
• Chemical Synthesis: Versatile reagent for constructing complex heterocycles via cyclization, coupling, and functional group transformation reactions.
• Academic & R&D: Utilized in university and institutional laboratories for methodological studies and discovery chemistry.
• Dye & Pigment Intermediate: Potential starting material for the synthesis of specialized colorants and imaging agents.

Basic Information

Product Name	2-Amino-4-(4-Chloro-Phenyl)-Thiophene-3-Carboxylic Acid Ethyl Ester
CAS No.	65234-09-5
Molecular Formula	C13H12ClNO2S
Molecular Weight	281.76 g/mol
Synonyms	Ethyl 2-Amino-4-(4-chlorophenyl)thiophene-3-carboxylate; 2-Amino-4-(p-chlorophenyl)thiophene-3-carboxylic Acid Ethyl Ester; 4-(4-Chlorophenyl)-2-aminothiophene-3-carboxylic Acid Ethyl Ester; 65234-09-5; AKOS BBS-00004379; 4-(4-Chlorophenyl)-2-aminothiophene-3-carboxylic acid ethyl ester; CS-0016226; NS00023892; EN300-73437; Ethyl 2-amino-4-(4-chlorophenyl)-3-thiophenecarboxylate
EINECS	Contact for details

Quality Control

Our 2-Amino-4-(4-Chloro-Phenyl)-Thiophene-3-Carboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) with detailed specifications are provided for each lot to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.