Description

(R)-2-Thienylglycine is a high-value, non-proteinogenic amino acid derivative featuring a thiophene side chain. This compound is a crucial chiral building block in the synthesis of complex pharmaceuticals and bioactive molecules. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing novel active ingredients, particularly in the areas of enzyme inhibitors and peptide mimetics. The product is supplied under stringent quality control to ensure batch-to-batch consistency for critical applications.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, especially protease inhibitors and other enzyme-targeted therapies.
• Peptidomimetics: Used to incorporate the thienyl moiety into peptide backbones to enhance metabolic stability, bioavailability, and binding affinity.
• Agrochemical Synthesis: Serves as a building block for creating novel herbicides, fungicides, and insecticides with specific chiral activity.
• Asymmetric Catalysis: Employed as a ligand precursor or chiral auxiliary in asymmetric synthetic transformations.
• Biochemical Research: Used in studies of amino acid metabolism, enzyme mechanisms, and as a substrate analog in biochemical assays.
• Material Science: Potential monomer for the synthesis of specialized polymers and functional materials.

Basic Information

Item	Details
Product Name	(R)-2-Thienylglycine
CAS No.	65058-23-3
Molecular Formula	C6H7NO2S
Molecular Weight	157.19 g/mol
Synonyms	(R)-2-Amino-2-(thiophen-2-yl)acetic acid; D-2-Thienylglycine; (R)-α-Amino-2-thiopheneacetic acid; (2R)-2-Amino-2-(thiophen-2-yl)ethanoic acid; (R)-2-Thienylglycine; (R)-TGA; (R)-2-(2-Thienyl)glycine
EINECS	Contact for details

Quality Control

Our (R)-2-Thienylglycine is manufactured under a quality management system and undergoes rigorous analytical testing to ensure it meets the high standards required for research and synthesis. Each batch is characterized by HPLC, chiral analysis, and NMR to confirm identity, purity, and enantiomeric excess. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment. We can support development projects with custom purity grades and analytical documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.