Description

4,5,6,6A,7,8-Hexahydro-1,10,11-Trimethoxy-6-Methylbenzo[6,7]Cyclohept[1,2,3-Ij]Isoquinoline-2,12-Diol is a complex, high-purity isoquinoline alkaloid derivative of significant interest in advanced organic synthesis. This compound matters as a sophisticated chemical building block for research and development in pharmaceutical discovery and fine chemical manufacturing. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel molecular entities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel alkaloid-based therapeutic agents and bioactive molecules.
• Organic Synthesis Building Block: Used in complex multi-step syntheses, particularly in constructing polycyclic frameworks common in natural product analogs.
• Biochemical Research: Serves as a reference standard or a starting material for investigating structure-activity relationships (SAR) in medicinal chemistry programs.
• Fine Chemical Production: Employed in the manufacture of high-value specialty chemicals requiring a specific, complex isoquinoline core structure.
• Academic & Industrial R&D: Utilized in research laboratories for methodological development and exploring new chemical transformations.

Basic Information

Product Name	4,5,6,6A,7,8-Hexahydro-1,10,11-Trimethoxy-6-Methylbenzo[6,7]Cyclohept[1,2,3-Ij]Isoquinoline-2,12-Diol
CAS No.	65022-65-3
Molecular Formula	C22H27NO5
Molecular Weight	385.46 g/mol
Synonyms	Benzo[6,7]cyclohept[1,2,3-ij]isoquinoline-2,12-diol, 4,5,6,6a,7,8-hexahydro-1,10,11-trimethoxy-6-methyl-; 6-Methyl-1,10,11-trimethoxy-4,5,6,6a,7,8-hexahydrobenzo[6,7]cyclohept[1,2,3-ij]isoquinoline-2,12-diol; Tetrahydroberberine derivative; Isoquinoline alkaloid intermediate; 65022-65-3; (6aS)-6-Methyl-1,10,11-trimethoxy-4,5,6,6a,7,8-hexahydrobenzo[6,7]cyclohept[1,2,3-ij]isoquinoline-2,12-diol
EINECS	Contact for details

Quality Control

Our 4,5,6,6A,7,8-Hexahydro-1,10,11-Trimethoxy-6-Methylbenzo[6,7]Cyclohept[1,2,3-Ij]Isoquinoline-2,12-Diol is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.