Description

(4Ar)-1,4,4A,5,6,7,8,8Aβ,9,9Aβ-Decahydro-3,4Aβ,5β-Trimethyl-2H-Benz[F]Indol-2-One is a complex, high-purity decahydrobenzindolone derivative, serving as a critical advanced intermediate in sophisticated organic synthesis. Its value lies in its unique, rigid polycyclic framework, which is essential for constructing complex molecular architectures with specific stereochemistry. This compound is primarily needed by research institutions and pharmaceutical development teams working on novel active pharmaceutical ingredients (APIs), particularly in the areas of alkaloid synthesis and the development of central nervous system (CNS) targeted therapies.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of complex natural product analogs and novel therapeutic agents.
• Alkaloid Synthesis: Used in the research and development of steroidal and triterpenoid alkaloid derivatives.
• Asymmetric Catalysis Research: Serves as a sophisticated ligand precursor or substrate in the development of new catalytic systems.
• Chemical Biology Probes: Utilized in the creation of molecular probes for studying enzyme mechanisms and receptor interactions.
• Process Chemistry Development: Employed in route scouting and optimization for the scalable production of high-value fine chemicals.
• Academic Research: A valuable compound for methodological studies in total synthesis and stereoselective transformations.

Basic Information

Product Name	(4Ar)-1,4,4A,5,6,7,8,8Aβ,9,9Aβ-Decahydro-3,4Aβ,5β-Trimethyl-2H-Benz[F]Indol-2-One
CAS No.	65012-44-4
Molecular Formula	C₁₆H₂₅NO
Molecular Weight	247.38 g/mol
Synonyms	Decahydro-3,4aβ,5β-trimethyl-2H-benz[f]indol-2-one; (4aR)-Decahydro-3,4aβ,5β-trimethyl-2H-benz[f]indol-2-one; 2H-Benz[f]indol-2-one, decahydro-3,4aβ,5β-trimethyl-, (4aR)-; 65012-44-4; (4aR)-1,4,4a,5,6,7,8,8aβ,9,9aβ-decahydro-3,4aβ,5β-trimethyl-2H-benz[f]indol-2-one; Trimethyl-decahydrobenzindolone; Decahydrotrimethylbenzindolone
EINECS	Contact for details

Quality Control

Our (4Ar)-1,4,4A,5,6,7,8,8Aβ,9,9Aβ-Decahydro-3,4Aβ,5β-Trimethyl-2H-Benz[F]Indol-2-One is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the exacting standards required for advanced research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity (by HPLC), and impurity profile is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The container should be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.