Description

(S)-1-Methyl-1,2,3,4-Tetrahydro-Isoquinoline Hydrochloride is a high-purity chiral building block and pharmaceutical intermediate of significant commercial importance. Its value lies in its role as a key synthon for the development of active pharmaceutical ingredients (APIs) and fine chemicals requiring a specific stereochemical configuration. This compound is essential for research and manufacturing in the pharmaceutical, agrochemical, and advanced material sectors, where precise molecular architecture is critical for function.

Application

• Pharmaceutical Intermediate: A crucial chiral precursor in the synthesis of various therapeutic agents, including central nervous system (CNS) drugs and receptor modulators.
• Asymmetric Synthesis: Serves as a versatile chiral scaffold or ligand in catalytic asymmetric reactions to produce enantiomerically pure compounds.
• Agrochemical Research: Used in the development of novel, stereospecific pesticides and herbicides with enhanced efficacy and selectivity.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances where the (S)-enantiomer is required.
• Academic & R&D: A valuable reagent for medicinal chemistry research, process development, and exploring new synthetic methodologies in university and industrial laboratories.

Basic Information

Product Name	(S)-1-Methyl-1,2,3,4-Tetrahydro-Isoquinoline Hydrochloride
CAS No.	64982-62-3
Molecular Formula	C10H14ClN
Molecular Weight	183.68 g/mol
Synonyms	(S)-1-Methyl-1,2,3,4-tetrahydroisoquinoline hydrochloride; (S)-1-Methyl-1,2,3,4-tetrahydroisoquinoline HCl; (S)-1-MTIQ hydrochloride; (S)-N-Methyl-1,2,3,4-tetrahydroisoquinoline hydrochloride; (S)-1-Methyl-3,4-dihydroisoquinoline hydrochloride; (S)-1-Methyl-THIQ HCl; (S)-MTIQ·HCl
EINECS	Contact for details

Quality Control

Our (S)-1-Methyl-1,2,3,4-Tetrahydro-Isoquinoline Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for pharmaceutical and fine chemical applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed and desiccated when not in use to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.