Description

(S)-1-Methyl-1,2,3,4-Tetrahydro-Isoquinoline is a chiral, non-racemic organic compound belonging to the tetrahydroisoquinoline class, a privileged scaffold in medicinal chemistry. This high-purity enantiomer is critical for research and development in asymmetric synthesis and pharmaceutical manufacturing. It serves as a valuable chiral building block and intermediate for scientists and manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of active pharmaceutical ingredients (APIs) targeting neurological and cardiovascular disorders.
• Asymmetric Catalyst Ligand: Used in the development of chiral ligands for transition metal catalysis to induce enantioselectivity in synthetic reactions.
• Agrochemical Research: Building block for creating novel, enantiomerically pure pesticides and herbicides with improved efficacy and environmental profiles.
• Neurological Research Tool: Serves as a reference standard and starting material for studying neurotransmitter analogs and receptor ligands.
• Fine Chemical Synthesis: Intermediate for producing specialty chemicals, flavors, and fragrances requiring high enantiomeric purity.
• Academic & R&D: Essential compound for methodological development in organic chemistry and medicinal chemistry research laboratories.

Basic Information

Product Name	(S)-1-Methyl-1,2,3,4-Tetrahydro-Isoquinoline
CAS No.	64982-61-2
Molecular Formula	C10H13N
Molecular Weight	147.22 g/mol
Synonyms	(S)-1-Methyl-1,2,3,4-tetrahydroisoquinoline; (S)-1-Methyl-3,4-dihydroisoquinoline; (S)-1-Methyl-1,2,3,4-tetrahydro-isoquinoline; (S)-1-MTIQ; (S)-N-Methyl-1,2,3,4-tetrahydroisoquinoline; (S)-1-Methyl-3,4-dihydro-2(1H)-isoquinoline; (1S)-1-Methyl-1,2,3,4-tetrahydroisoquinoline
EINECS	Contact for details

Quality Control

Our (S)-1-Methyl-1,2,3,4-Tetrahydro-Isoquinoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and GMP-grade synthesis. A detailed Certificate of Analysis (COA) specifying identity, purity, enantiomeric excess, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. Due to its sensitivity to oxidation, the container should be kept sealed under positive pressure of inert gas after opening.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.