Description

Butyric-3,3-D2 Acid is a deuterium-labeled isotopologue of butyric acid, specifically deuterated at the 3,3-positions. This high-purity stable isotope-labeled compound is essential for advanced analytical and research applications where precise molecular tracking is required. It is primarily utilized by researchers and scientists in the pharmaceutical, agrochemical, and metabolic research sectors for use as an internal standard in mass spectrometry, NMR spectroscopy, and kinetic isotope effect studies.

Application

• Internal Standard for Mass Spectrometry (MS): Provides accurate quantification in GC-MS and LC-MS analyses of butyric acid and related metabolites in complex biological matrices.
• NMR Spectroscopy: Serves as a valuable probe in nuclear magnetic resonance studies for mechanistic investigations and structural elucidation.
• Metabolic Pathway Tracing: Used in pharmacokinetic and metabolic flux studies to track the absorption, distribution, and metabolism of butyrate.
• Pharmaceutical Research: Employed in the development and validation of analytical methods for drug substances and impurities.
• Nutritional and Microbiome Research: Facilitates the study of short-chain fatty acid (SCFA) production and gut microbiota interactions.
• Chemical Synthesis Intermediate: Acts as a labeled building block for the synthesis of more complex deuterated compounds.

Basic Information

Product Name	Butyric-3,3-D2 Acid
CAS No.	64833-96-1
Molecular Formula	C₄H₆D₂O₂
Molecular Weight	90.11 g/mol
Synonyms	Butanoic-3,3-d2 Acid; [3,3-²H₂]Butyric Acid; Deuterated Butyric Acid; 3,3-Dideuterobutanoic Acid; Butyric Acid-d2; n-Butyric-3,3-D2 Acid; Propyl-3,3-D2 Carboxylic Acid; 64833-96-1
EINECS	Contact for details

Quality Control

Every batch of Butyric-3,3-D2 Acid is produced and analyzed under strict quality management protocols to ensure exceptional isotopic and chemical purity, critical for sensitive research applications. We provide comprehensive Certificates of Analysis (COA) detailing isotopic enrichment (D atom %), chemical purity by HPLC, and identification data. Our quality commitment aligns with the stringent requirements of research and development laboratories.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated place, away from heat sources and incompatible materials. Due to its nature as a strong acid/organic solvent and high volatility, ensure containers are securely sealed to prevent evaporation and are handled with appropriate precautions in a fume hood.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment (D atom %)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.