Description

Ethyl (4S,5R,6S)-6-Hydroxy-3-Methoxy-1,6-Dimethyl-4-Phenyl-5,7-Dihydro -4H-Indazole-5-Carboxylate is a high-purity, chiral indazole derivative of significant interest in advanced organic synthesis. This compound serves as a critical pharmaceutical intermediate and a versatile building block for the development of novel active molecules. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the discovery and process development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of complex drug candidates, particularly in oncology and CNS research.
• Chemical Research & Development: Used as a sophisticated building block for constructing novel heterocyclic compounds and exploring new chemical spaces.
• Process Chemistry: Employed in route scouting and optimization for the scalable production of target active pharmaceutical ingredients (APIs).
• Asymmetric Synthesis: Utilized in stereoselective reactions due to its defined (4S,5R,6S) configuration, enabling the creation of enantiomerically pure products.
• Reference Standard: Serves as a high-purity analytical standard for method development and quality control in pharmaceutical manufacturing.

Basic Information

Product Name	Ethyl (4S,5R,6S)-6-Hydroxy-3-Methoxy-1,6-Dimethyl-4-Phenyl-5,7-Dihydro -4H-Indazole-5-Carboxylate
CAS No.	64670-59-3
Molecular Formula	C19H24N2O4
Molecular Weight	344.41 g/mol
Synonyms	Ethyl 6-hydroxy-3-methoxy-1,6-dimethyl-4-phenyl-4,5,6,7-tetrahydro-1H-indazole-5-carboxylate; (4S,5R,6S)-Ethyl 6-hydroxy-3-methoxy-1,6-dimethyl-4-phenyl-5,7-dihydro-4H-indazole-5-carboxylate; 5,7-Dihydro-4H-indazole-5-carboxylic acid, 6-hydroxy-3-methoxy-1,6-dimethyl-4-phenyl-, ethyl ester, (4S,5R,6S)-; 64670-59-3; Ethyl 6-Hydroxy-3-Methoxy-1,6-Dimethyl-4-Phenyl-4,5,6,7-Tetrahydro-1H-Indazole-5-Carboxylate
EINECS	Contact for details

Quality Control

Our Ethyl (4S,5R,6S)-6-Hydroxy-3-Methoxy-1,6-Dimethyl-4-Phenyl-5,7-Dihydro -4H-Indazole-5-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The container should be kept in a well-ventilated area and protected from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.