Description

Ethyl (4S,5R,6S)-4-(3,4-Dimethoxyphenyl)-6-Hydroxy-6-Methyl-3-Oxo-2,4,5,7-Tetrahydro-1H-Indazole-5-Carboxylate is a high-purity, stereochemically defined indazole derivative of significant interest in advanced organic synthesis. This compound matters as a sophisticated chiral building block and a key intermediate for the research and development of novel pharmaceutical agents. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries working on complex molecule synthesis.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral precursor in the synthesis of potential drug candidates targeting complex biological pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic entities.
• Process Chemistry Development: Employed in scaling up synthetic routes for active pharmaceutical ingredients (APIs) under Good Manufacturing Practice (GMP) conditions.
• Asymmetric Synthesis: Acts as a valuable chiral scaffold for constructing molecules with defined stereochemistry in advanced organic transformations.
• Reference Standard: Utilized as an analytical standard for quality control and method validation in pharmaceutical analysis.
• Biochemical Research: Investigated as a potential tool compound or probe for studying enzyme inhibition or receptor binding.

Basic Information

Product Name	Ethyl (4S,5R,6S)-4-(3,4-Dimethoxyphenyl)-6-Hydroxy-6-Methyl-3-Oxo-2,4,5,7-Tetrahydro-1H-Indazole-5-Carboxylate
CAS No.	64670-44-6
Molecular Formula	C19H24N2O6
Molecular Weight	376.41 g/mol
Synonyms	Ethyl 4-(3,4-dimethoxyphenyl)-6-hydroxy-6-methyl-3-oxo-2,4,5,7-tetrahydro-1H-indazole-5-carboxylate; (4S,5R,6S)-Ethyl 4-(3,4-dimethoxyphenyl)-6-hydroxy-6-methyl-3-oxo-1,4,5,7-tetrahydro-2H-indazole-5-carboxylate; 1H-Indazole-5-carboxylic acid, 4-(3,4-dimethoxyphenyl)-2,4,5,7-tetrahydro-6-hydroxy-6-methyl-3-oxo-, ethyl ester, (4S,5R,6S)-; Ethyl 4-(3,4-dimethoxyphenyl)-6-hydroxy-6-methyl-3-oxo-1,4,5,7-tetrahydro-2H-indazole-5-carboxylate; 64670-44-6; Chiral indazole ester; Tetrahydroindazole derivative.
EINECS	Contact for details

Quality Control

Our Ethyl (4S,5R,6S)-4-(3,4-Dimethoxyphenyl)-6-Hydroxy-6-Methyl-3-Oxo-2,4,5,7-Tetrahydro-1H-Indazole-5-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure high chemical and stereochemical purity suitable for research and development applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.