Description

(R)-1-Phenyl-2-Propyn-1-Ol is a chiral propargylic alcohol building block of significant importance in asymmetric synthesis. Its value lies in its role as a versatile intermediate for constructing complex molecules with defined stereochemistry. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly for developing active pharmaceutical ingredients (APIs) and advanced materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of various APIs, including potential antiviral, anticancer, and neurological agents.
• Asymmetric Catalysis: Used as a ligand precursor or a substrate in catalytic asymmetric reactions to create enantiomerically pure compounds.
• Fine Chemical Synthesis: Employed in the production of specialty chemicals, flavors, fragrances, and advanced organic materials.
• Academic & Industrial R&D: Serves as a critical starting material for method development and exploring new synthetic pathways in organic chemistry.
• Agrochemical Research: Potential intermediate in the development of novel, chiral pesticides and herbicides.

Basic Information

Product Name	(R)-1-Phenyl-2-Propyn-1-Ol
CAS No.	64599-56-0
Molecular Formula	C9H8O
Molecular Weight	132.16 g/mol
Synonyms	(R)-1-Phenylprop-2-yn-1-ol; (R)-α-Hydroxymethylphenylacetylene; (R)-Phenylpropargyl alcohol; (R)-1-Hydroxy-1-phenyl-2-propyne; (R)-1-Phenyl-2-propynol; (R)-(-)-1-Phenyl-2-propyn-1-ol; (R)-PGA
EINECS	Contact for details

Quality Control

Our (R)-1-Phenyl-2-Propyn-1-Ol is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis, to ensure it meets the high standards required for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.