Description

Ethyl-2,2,2-D3-Amine Hcl is a deuterium-labeled derivative of ethylamine hydrochloride, a valuable isotopically labeled building block. This compound is essential for researchers and manufacturers requiring precise molecular tracking and analysis in complex systems. It is primarily used in the pharmaceutical, agrochemical, and analytical chemistry industries for applications such as internal standards, metabolic studies, and the synthesis of labeled active pharmaceutical ingredients (APIs).

Application

• Deuterated Internal Standards: Used in quantitative mass spectrometry (LC-MS, GC-MS) for accurate drug and metabolite analysis in pharmacokinetic and bioanalytical studies.
• Metabolic Pathway Tracing: Serves as a stable isotope tracer in drug metabolism and disposition (DMPK) research to elucidate biotransformation pathways.
• Synthesis of Labeled APIs: Acts as a key deuterium-labeled synthon in the development of deuterated drug candidates, which can offer improved metabolic profiles.
• NMR Spectroscopy: Employed as a reagent or intermediate in nuclear magnetic resonance (NMR) studies for structural analysis and mechanistic investigations.
• Agrochemical Research: Used in the development and environmental fate studies of isotopically labeled pesticides and herbicides.
• Chemical Reaction Mechanism Studies: Aids in probing reaction mechanisms and kinetics in synthetic organic chemistry due to its isotopic label.

Basic Information

Product Name	Ethyl-2,2,2-D3-Amine Hcl
CAS No.	64585-12-2
Molecular Formula	C2D5ClN
Molecular Weight	86.56 g/mol
Synonyms	Deuterated Ethylamine Hydrochloride; Ethyl-d5-amine hydrochloride; (2,2,2-D3)Ethylamine hydrochloride; Ethylamine-d5 hydrochloride; Ethylamine-2,2,2-d3 hydrochloride; Aminoethane-d5 hydrochloride; Monoethyl-d5-amine hydrochloride; NSC 760463
EINECS	Contact for details

Quality Control

Our Ethyl-2,2,2-D3-Amine Hcl is produced under strict quality management systems. Each batch is subjected to rigorous analytical testing, including NMR, HPLC, and mass spectrometry, to confirm isotopic purity, chemical purity, and identity. We provide comprehensive Certificates of Analysis (COA) detailing all specifications, ensuring traceability and compliance with your research or cGMP guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-content)	≥ 98 atom % D
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.