Description

1,7-Dicarba-Closo-Dodecaborane-9-Yl-Thiol, 9-Mercapto-1,7-Dicarbadodecaborane (12) is a specialized organoborane compound featuring a reactive thiol (-SH) group, making it a valuable building block for advanced materials and pharmaceutical research. Its unique carborane cage structure provides exceptional thermal and chemical stability, while the thiol functionality enables robust covalent attachment to surfaces and other molecules. This compound is essential for researchers and manufacturers in the fields of boron neutron capture therapy (BNCT), polymer modification, and the development of novel inorganic-organic hybrid materials.

Application

• Boron Neutron Capture Therapy (BNCT): As a key intermediate for synthesizing tumor-targeting boron carriers due to its high boron content and modifiable thiol group.
• Surface Functionalization: For creating self-assembled monolayers (SAMs) on gold, silver, and other metal surfaces to alter surface properties like wettability, corrosion resistance, and biocompatibility.
• Polymer Science: Acting as a cross-linking agent or modifier to incorporate boron clusters into polymers, enhancing their thermal stability and radiation shielding properties.
• Materials Chemistry: Synthesis of novel inorganic-organic hybrid materials, metal-organic frameworks (MOFs), and nanocomposites with tailored functionalities.
• Catalysis: As a ligand precursor for creating novel transition metal catalysts with unique steric and electronic properties imparted by the carborane cage.
• Pharmaceutical Intermediates: Used in the research and development of new drug candidates, particularly where the stable carborane unit can improve metabolic stability.

Basic Information

Product Name	1,7-Dicarba-Closo-Dodecaborane-9-Yl-Thiol, 9-Mercapto-1,7-Dicarbadodecaborane (12)
CAS No.	64493-44-3
Molecular Formula	C2H12B10S
Molecular Weight	173.82 g/mol
Synonyms	9-Mercapto-1,7-dicarbadodecaborane(12); 9-SH-1,7-dicarbadodecaborane; 1,7-Dicarbadodecaborane-9-thiol; 9-Mercapto-m-carborane; m-Carborane-9-thiol; 9-Thiol-m-carborane; HS-m-carborane; Mercapto carborane
EINECS	Contact for details

Quality Control

Our production of 1,7-Dicarba-Closo-Dodecaborane-9-Yl-Thiol adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is characterized using advanced analytical techniques including NMR, HPLC, and IR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent oxidation of the thiol group.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.